EatSouth Buffalo

Wiseguys

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Address: 1965 Seneca St.
Getting there: Metro Bus 15
Hours: Sun-Wed 11AM-11PM, Thu-Sat 11AM-4AM
Website: wiseguysbuffalo.com (opens in a new tab)

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Listing from Wikivoyage: Buffalo/South Buffalo, CC BY-SA 4.0.

Updated 28 Sept 2026. Something wrong? Tell us.

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EatSouth Buffalo
Tops
1989 Seneca St.
Daily 6AM-11PM
EatSouth Buffalo
Francesca's
If the name of this place didn't clue you in to what kind of food is served here, the exterior sure will: this building screams "Italy" in the heart of Irish South Buffalo, from the bright orange stucco walls up to the red tile roof. Classic and contemporary fare with a local twist is the name of the game at Francesca's, served in an upscale, trattoria-style ambience: the "classic" half of the equation dominated among the main courses, a standard but well-executed roster of homestyle red-sauce favorites, while the "local twists" come into play with the appetizers, especially the house special "Unstuffed Hot Pepper Soup", an ingenious take on the local favorite where spicy Anaheim peppers come in a creamy broth made with ricotta cheese. The dining room is spacious yet intimate, but on summer nights the back patio is the place to be.
Tue-Sun 11AM-10PM$15-45
BuySouth Buffalo
South Buffalo Wheelhouse
If you're in the market for a brand new bike, the friendly folks at this Seneca Street bike shop will be glad to sell you one, but wouldn't you rather be the proud new owner of a gently used vintage bike from the 1980s or '90s, lovingly restored and sold at a decent price? And if you already own a bike and are just looking for a tune-up, you're in luck: the real specialty here is expert repairs and installations done with a smile (check their website for their "menu of services"). Best of all, the bevy of discounts you get by becoming a member makes the $135 annual fee worth it even if you're not planning to stay in town for an extended time.
Tue-Fri 10AM-6PM, Sat 10AM-4PM, shorter hours in winter
EatSouth Buffalo
Emergency Pizza
1870 Seneca St.
Mon-Thu 11AM-2AM, Fri Sat 11AM-4AM, Sun 11AM-midnight